If you’re dreaming of a soft, berry-studded slice that feels like sunshine and comfort in every bite, then Blueberry Cream Cheese Bread delivers in the most delicious way. This moist loaf marries bursts of juicy blueberries with rich, tangy cream cheese for a treat that tastes just as lovely as it looks. Whether you serve it for breakfast, as a snack, or sneak a piece for dessert, it’s one of those recipes you’ll come back to anytime you need a little sweetness in your day.

Ingredients You’ll Need
The beauty of Blueberry Cream Cheese Bread lies in its straightforward ingredients—each one essential for yielding its trademark flavor, pillowy crumb, and irresistible color. These staples combine to create a fresh, bakery-worthy loaf right in your own kitchen.
- All-purpose flour: Provides the structure your bread depends on, giving it a tender but sturdy crumb.
- Baking powder: Adds lift and helps the bread rise tall and proud.
- Baking soda: Works with the buttermilk to tenderize and help the bread develop that golden hue.
- Salt: Enhances the sweetness and deepens all the flavors.
- Unsalted butter (softened): Lends rich flavor and the irresistible melt-in-your-mouth texture.
- Cream cheese (softened): The secret to extra-moist bread with a faint tang and creamy crumb.
- Granulated sugar: Gives sweetness and helps keep the loaf moist.
- Large eggs: Bind the mixture together and add tenderness.
- Vanilla extract: Brings warmth and a subtly sweet aroma to the bread.
- Buttermilk: Makes the loaf extra soft and slightly tangy, balancing the sweet berries.
- Fresh or frozen blueberries: Jewel-like bursts of fruit flavor throughout every slice; use them straight from the freezer if frozen.
- Flour (for coating blueberries): Prevents the berries from sinking to the bottom so each piece is perfectly dotted with color.
How to Make Blueberry Cream Cheese Bread
Step 1: Prepare Your Pan and Oven
Begin by preheating your oven to 350°F (175°C) so it’s hot and ready when your batter is assembled. Either grease a 9×5-inch loaf pan or line it with parchment paper for easy release—trust me, nothing’s sadder than a delicious loaf stuck to the pan.
Step 2: Whisk the Dry Ingredients
In a medium bowl, whisk together the all-purpose flour, baking powder, baking soda, and salt. This quick step ensures that your leavening agents are well-distributed, setting the stage for an even, light crumb in every bite of your Blueberry Cream Cheese Bread.
Step 3: Cream the Butter and Cream Cheese
Grab a large bowl and beat the softened butter with the cream cheese until the mixture is smooth and creamy. This combo promises both richness and a delicate tang—don’t rush this part, as a proper creaming is key to tender bread.
Step 4: Add Sugar, Eggs, and Vanilla
Next, add the sugar to your creamed mixture and continue beating until light and fluffy, about 2–3 minutes. Then, beat in the eggs one at a time, mixing well after each addition, followed by the vanilla extract. This keeps your batter lush and cohesive for a dreamy loaf.
Step 5: Combine the Wet and Dry Mixtures
Add the dry ingredients in three additions, alternating with the buttermilk—starting and ending with the flour mixture. Slightly mix after each addition, just until combined. This step gives your Blueberry Cream Cheese Bread its soft crumb without overworking the batter.
Step 6: Coat and Fold in the Blueberries
In a small bowl, toss your blueberries with a tablespoon of flour, especially important if they’re frozen. This gentle flour coat helps them stay evenly distributed throughout the loaf instead of sinking to the bottom. Gently fold the coated blueberries into the batter, being careful not to crush them.
Step 7: Bake the Bread
Pour the batter into your prepared loaf pan and smooth out the top. Slide it into the preheated oven and bake for 55 to 65 minutes. Your kitchen will fill with the sweetest aroma! The loaf is done when a toothpick inserted in the center comes out clean or with just a few moist crumbs.
Step 8: Cool and Slice
Let your richly golden Blueberry Cream Cheese Bread cool in the pan for about 10 minutes before transferring it to a wire rack to finish cooling completely. This rest sets the crumb and ensures the slices come out beautifully intact—definitely worth a moment’s patience.
How to Serve Blueberry Cream Cheese Bread

Garnishes
A simple dusting of powdered sugar is classic, but for something extra special, you can drizzle a quick glaze made from powdered sugar and a splash of milk or lemon juice. Add a few extra fresh blueberries on top for a pop of color, or even scatter on some lemon zest to bring a hint of bright citrus.
Side Dishes
Pair a thick slice of Blueberry Cream Cheese Bread with a bowl of Greek yogurt and a handful of granola for a complete breakfast. For a brunch spread, serve it alongside crisp bacon, scrambled eggs, or a platter of sliced fresh fruit. Coffee and tea are its best friends!
Creative Ways to Present
You can transform slices of this bread into a beautiful breakfast trifle by layering with whipped cream and extra berries, or cut it into cubes and toast as “shortcake croutons” for a fun dessert topping. For a fancy dessert plate, serve warm with a scoop of vanilla ice cream and a drizzle of blueberry compote.
Make Ahead and Storage
Storing Leftovers
Blueberry Cream Cheese Bread stays remarkably moist for up to three days when stored in an airtight container at room temperature. If your kitchen is very warm, refrigerate it to keep it fresh, but always allow it to come to room temperature before serving for best flavor and texture.
Freezing
This bread freezes beautifully! Once completely cooled, wrap the loaf—or individual slices—in plastic wrap, then foil. Store in a freezer bag for up to three months. Thaw overnight in the refrigerator or on the counter for a few hours before enjoying.
Reheating
To bring back that just-baked warmth and softness, gently reheat slices in the microwave for 10–15 seconds or toast them lightly in a toaster oven. If serving guests, a quick warm-up in a 300°F oven for 5–8 minutes revives the freshness and makes your house smell amazing again!
FAQs
Can I use frozen blueberries instead of fresh?
Absolutely—frozen blueberries work wonderfully here. Just add them to the batter straight from the freezer without thawing, and be sure to coat them in flour to keep them from sinking or turning the batter blue.
Is there a substitute for buttermilk?
If you don’t have buttermilk on hand, stir 1 1/2 teaspoons of lemon juice or vinegar into 1/2 cup of milk and let it sit for a few minutes. This homemade version works just as well in yielding a soft, tender crumb.
Why do I need to coat the blueberries in flour?
Tossing the blueberries with flour before folding them into the batter helps suspend the fruit throughout the loaf. This simple trick prevents the berries from sinking straight to the bottom and ensures every slice boasts a beautiful blueberry distribution.
Can I make Blueberry Cream Cheese Bread gluten-free?
Yes! Swap the all-purpose flour for your favorite cup-for-cup gluten-free flour blend. Keep in mind that the texture may vary slightly, but the flavor will still be delicious and satisfying.
What’s the best way to glaze this bread?
Mix together 1/2 cup of powdered sugar with just 1–2 teaspoons of milk or lemon juice until smooth, then drizzle over your cooled Blueberry Cream Cheese Bread for an elegant and sweet finish.
Final Thoughts
I truly hope you give this Blueberry Cream Cheese Bread a try—it’s the kind of recipe that brightens any day and brings smiles with every bite. Whether enjoyed fresh from the oven or tucked away for tomorrow’s snack, it’s sure to become your new go-to loaf. Happy baking, and don’t forget to share a slice with someone you love!
